Quote:
Originally Posted by Tentaikun
Been having bad anxiety and need more and more benzodiazepine. Those antidepressants doesn't really work and benzodiazepine helps but hard to get. Feel like trying buy online but scare not real thing. Any recommendation what should i do?
Thanks.
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https://www.psychiatrictimes.com/vie...-risk-dementia
Consequences of Benzodiazepine Use
The use of benzodiazepines is known to be associated with poor outcomes.3,6-8 One study found that benzodiazepine use was associated with greater risk for hospitalizations, emergency department visits, outpatient visits, and higher health care costs.3 Another study found the overdose death rate increased due to benzodiazepine use from 0.58 to 3.07 per 100,000 adults between 1996 and 2013.6 Benzodiazepines use is also associated with an increased risk of falls among older adults.7 Additionally, the use of benzodiazepines is associated with a 60% to 80% increase in the risk of traffic accidents.8 The co-ingestion of benzodiazepines and alcohol is associated with a 7.7-fold increased risk for traffic accidents.
Table. Studies Showing Positive Association Between Benzodiazepine Use and the Risk of Dementia
Now, there is also emerging evidence that the use of benzodiazepines may increase the risk for developing dementia among older adults.9-11 This review evaluates the evidence from the literature on the association between benzodiazepine use and the risk for developing dementia.
Exploring the Literature and Evidence
A review of the literature indicates that there is a total of 15 studies that have evaluated the association between benzodiazepine use and the development of dementia.12-26 Four of the 15 studies were published prior to 201012-15 and 11 of the studies were published since 2010.16-26
Although there are no randomized controlled trials (RCTs) looking at the association between benzodiazepine use and the risk for dementia, 6 prospective cohort studies,12,14,17,22,23,25 6 case control studies,13,15,16,20,21,24 and 1 retrospective cohort study18 explore the relationship. Two studies had both a prospective cohort and a case control component.19,26 Three of the studies were conducted in France,13,19,22 3 in Taiwan,15,16,18 3 in Canada,14,20,25 2 in the United Kingdom,17, 21 and 1 each in Sweden,14 the United States,23 Switzerland,24 and Denmark.26
Of the 15 studies, 8 showed a positive association between benzodiazepine use and the development of dementia.13,15,16-20,22 Of these 8 studies, 2 were prospective cohort studies,17,22 4 were case control studies,13,15,16,20 and 1 was a retrospective cohort study.18 One positive study had a prospective cohort and a case control arm to the study.19